YOR368W
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| Systematic name | YOR368W |
| Gene name | RAD17 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:1026843..1028048 |
| Primary SGDID | S000005895 |
Description of YOR368W: Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; with Mec3p and Ddc1p, forms a clamp that is loaded onto partial duplex DNA; homolog of human and S. pombe Rad1 and U. maydis Rec1 proteins[1][2][3][4]
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References
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- ↑ Lydall D, et al. (1996) A meiotic recombination checkpoint controlled by mitotic checkpoint genes. Nature 383(6603):840-3 SGD PMID 8893012
- ↑ Majka J and Burgers PM (2003) Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint. Proc Natl Acad Sci U S A 100(5):2249-54 SGD PMID 12604797
- ↑ Parker AE, et al. (1998) A human homologue of the Schizosaccharomyces pombe rad1+ checkpoint gene encodes an exonuclease. J Biol Chem 273(29):18332-9 SGD PMID 9660799
- ↑ Shinohara M, et al. (2003) The mitotic DNA damage checkpoint proteins Rad17 and Rad24 are required for repair of double-strand breaks during meiosis in yeast. Genetics 164(3):855-65 SGD PMID 12871899
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