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Systematic name YOR360C
Gene name PDE2
Aliases SRA5
Feature type ORF, Verified
Coordinates Chr XV:1014821..1013241
Primary SGDID S000005887

Description of YOR360C: High-affinity cyclic AMP phosphodiesterase, component of the cAMP-dependent protein kinase signaling system, protects the cell from extracellular cAMP, contains readthrough motif surrounding termination codon[1][2][3][4]


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  1. Namy O, et al. (2002) Translational readthrough of the PDE2 stop codon modulates cAMP levels in Saccharomyces cerevisiae. Mol Microbiol 43(3):641-52 SGD PMID 11929521
  2. Nikawa J, et al. (1987) Cloning and characterization of the low-affinity cyclic AMP phosphodiesterase gene of Saccharomyces cerevisiae. Mol Cell Biol 7(10):3629-36 SGD PMID 2824992
  3. Sass P, et al. (1986) Cloning and characterization of the high-affinity cAMP phosphodiesterase of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 83(24):9303-7 SGD PMID 3025832
  4. Wilson RB, et al. (1993) The pde2 gene of Saccharomyces cerevisiae is allelic to rca1 and encodes a phosphodiesterase which protects the cell from extracellular cAMP. FEBS Lett 325(3):191-5 SGD PMID 8391474

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