YOR266W

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Systematic name YOR266W
Gene name PNT1
Aliases
Feature type ORF, Verified
Coordinates Chr XV:821023..822294
Primary SGDID S000005792


Description of YOR266W: Mitochondrial integral inner membrane protein involved in membrane insertion of C-terminus of Cox2p, interacts genetically and physically with Cox18p; deletion mutant sensitive to the anti-Pneumocystis carinii drug pentamidine[1][2][3]




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References

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  1. He S and Fox TD (1999) Mutations affecting a yeast mitochondrial inner membrane protein, pnt1p, block export of a mitochondrially synthesized fusion protein from the matrix. Mol Cell Biol 19(10):6598-607 SGD PMID 10490599
  2. Ludewig G and Staben C (1994) Characterization of the PNT1 pentamidine resistance gene of Saccharomyces cerevisiae. Antimicrob Agents Chemother 38(12):2850-6 SGD PMID 7695273
  3. Saracco SA and Fox TD (2002) Cox18p is required for export of the mitochondrially encoded Saccharomyces cerevisiae Cox2p C-tail and interacts with Pnt1p and Mss2p in the inner membrane. Mol Biol Cell 13(4):1122-31 SGD PMID 11950926

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