YOR258W
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| Systematic name | YOR258W |
| Gene name | HNT3 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:811671..812324 |
| Primary SGDID | S000005784 |
Description of YOR258W: DNA 5' AMP hydrolase involved in DNA repair; member of the histidine triad (HIT) superfamily of nucleotide-binding proteins; homolog of Aprataxin, a Hint related protein that is mutated in individuals with ataxia with oculomotor apraxia[1][2][3]
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References
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- ↑ Ahel I, et al. (2006) The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates. Nature 443(7112):713-6 SGD PMID 16964241
- ↑ Bieganowski P, et al. (2002) Adenosine monophosphoramidase activity of Hint and Hnt1 supports function of Kin28, Ccl1, and Tfb3. J Biol Chem 277(13):10852-60 SGD PMID 11805111
- ↑ Daley JM, et al. (2010) Genetic interactions between HNT3/Aprataxin and RAD27/FEN1 suggest parallel pathways for 5' end processing during base excision repair. DNA Repair (Amst) 9(6):690-9 SGD PMID 20399152
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