YOR250C
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| Systematic name | YOR250C |
| Gene name | CLP1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:802307..800970 |
| Primary SGDID | S000005776 |
Description of YOR250C: Component of the cleavage and polyadenylation factor I (CF I); CF 1, composed of the CF 1A complex (Rna14p, Rna15p, Clp1p, Pcf11p) and Hrp1, is involved in cleavage and polyadenylation of mRNA 3' ends; involved in both the endonucleolyitc cleavage and polyadenylation steps of mRNA 3'-end maturation[1][2][3]
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References
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- ↑ Gordon J, et al. (2011) Reconstitution of CF IA form overexpressed subunits reveals stoichiometry and provides insight into molecular topology. Biochemistry () SGD PMID 22026644
- ↑ Gross S and Moore C (2001) Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I. Proc Natl Acad Sci U S A 98(11):6080-5 SGD PMID 11344258
- ↑ Minvielle-Sebastia L, et al. (1997) The major yeast poly(A)-binding protein is associated with cleavage factor IA and functions in premessenger RNA 3'-end formation. Proc Natl Acad Sci U S A 94(15):7897-902 SGD PMID 9223284
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