YOR244W

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Systematic name YOR244W
Gene name ESA1
Aliases TAS1
Feature type ORF, Verified
Coordinates Chr XV:792531..793868
Primary SGDID S000005770


Description of YOR244W: Catalytic subunit of the histone acetyltransferase complex (NuA4) that acetylates four conserved internal lysines of histone H4 N-terminal tail; required for cell cycle progression and transcriptional silencing at the rDNA locus[1][2][3]




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References

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  1. Allard S, et al. (1999) NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM-related cofactor Tra1p. EMBO J 18(18):5108-19 SGD PMID 10487762
  2. Clarke AS, et al. (2006) Distinct roles for the essential MYST family HAT Esa1p in transcriptional silencing. Mol Biol Cell 17(4):1744-57 SGD PMID 16436512
  3. Smith ER, et al. (1998) ESA1 is a histone acetyltransferase that is essential for growth in yeast. Proc Natl Acad Sci U S A 95(7):3561-5 SGD PMID 9520405

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