YOR178C
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| Systematic name | YOR178C |
| Gene name | GAC1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:670241..667860 |
| Primary SGDID | S000005704 |
Description of YOR178C: Regulatory subunit for Glc7p type-1 protein phosphatase (PP1), tethers Glc7p to Gsy2p glycogen synthase, binds Hsf1p heat shock transcription factor, required for induction of some HSF-regulated genes under heat shock[1][2][3][4]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [2] [5]
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References
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- ↑ Nigavekar SS, et al. (2002) Glc8 is a glucose-repressible activator of Glc7 protein phosphatase-1. Arch Biochem Biophys 404(1):71-9 SGD PMID 12127071
- ↑ 2.0 2.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ Williams-Hart T, et al. (2002) Protein phosphatase type 1 regulates ion homeostasis in Saccharomyces cerevisiae. Genetics 160(4):1423-37 SGD PMID 11973298
- ↑ Wu X, et al. (2001) Characterization of Gac1p, a regulatory subunit of protein phosphatase type I involved in glycogen accumulation in Saccharomyces cerevisiae. Mol Genet Genomics 265(4):622-35 SGD PMID 11459182
- ↑ submitted by Jeff Ubersax on 2004-01-29
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