YOR165W
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| Systematic name | YOR165W |
| Gene name | SEY1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:644566..646896 |
| Primary SGDID | S000005691 |
Description of YOR165W: Dynamin-like GTPase that mediates homotypic ER fusion; has a role in ER morphology; interacts physically and genetically with Yop1p and Rtn1p; functional ortholog of the human atlastin ATL1, defects in which cause a form of the human disease hereditary spastic paraplegia; homolog of Arabidopsis RHD3[1][2][3]
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References
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- ↑ Anwar K, et al. (2012) The dynamin-like GTPase Sey1p mediates homotypic ER fusion in S. cerevisiae. J Cell Biol 197(2):209-17 SGD PMID 22508509
- ↑ Brands A and Ho TH (2002) Function of a plant stress-induced gene, HVA22. Synthetic enhancement screen with its yeast homolog reveals its role in vesicular traffic. Plant Physiol 130(3):1121-31 SGD PMID 12427979
- ↑ Hu J, et al. (2009) A class of dynamin-like GTPases involved in the generation of the tubular ER network. Cell 138(3):549-61 SGD PMID 19665976
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