YOR117W

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Systematic name YOR117W
Gene name RPT5
Aliases YTA1
Feature type ORF, Verified
Coordinates Chr XV:545029..546333
Primary SGDID S000005643


Description of YOR117W: One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; recruited to the GAL1-10 promoter region upon induction of transcription; similar to human TBP1[1][2][3][4][5]




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References

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  1. Glickman MH, et al. (1998) The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol 18(6):3149-62 SGD PMID 9584156
  2. Glickman MH, et al. (1999) Functional analysis of the proteasome regulatory particle. Mol Biol Rep 26(1-2):21-8 SGD PMID 10363642
  3. Gonzalez F, et al. (2002) Recruitment of a 19S proteasome subcomplex to an activated promoter. Science 296(5567):548-50 SGD PMID 11964484
  4. Rubin DM, et al. (1998) Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome. EMBO J 17(17):4909-19 SGD PMID 9724628
  5. Schnall R, et al. (1994) Identification of a set of yeast genes coding for a novel family of putative ATPases with high similarity to constituents of the 26S protease complex. Yeast 10(9):1141-55 SGD PMID 7754704

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