YOR046C

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Systematic name YOR046C
Gene name DBP5
Aliases RAT8
Feature type ORF, Verified
Coordinates Chr XV:415907..414459
Primary SGDID S000005572


Description of YOR046C: Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family; involved in mRNA export from the nucleus; involved in translation termination; ATP/ADP cycling is regulated by Gle1p and Nup159p[1][2][3][4]




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References

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  1. Estruch F and Cole CN (2003) An early function during transcription for the yeast mRNA export factor Dbp5p/Rat8p suggested by its genetic and physical interactions with transcription factor IIH components. Mol Biol Cell 14(4):1664-76 SGD PMID 12686617
  2. Gross T, et al. (2007) The DEAD-box RNA helicase Dbp5 functions in translation termination. Science 315(5812):646-9 SGD PMID 17272721
  3. Noble KN, et al. (2011) The Dbp5 cycle at the nuclear pore complex during mRNA export II: nucleotide cycling and mRNP remodeling by Dbp5 are controlled by Nup159 and Gle1. Genes Dev 25(10):1065-77 SGD PMID 21576266
  4. Tseng-Rogenski SS, et al. (2003) Functional conservation of Dhh1p, a cytoplasmic DExD/H-box protein present in large complexes. Nucleic Acids Res 31(17):4995-5002 SGD PMID 12930949

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