YOR028C
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| Systematic name | YOR028C |
| Gene name | CIN5 |
| Aliases | HAL6, YAP4 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:384420..383533 |
| Primary SGDID | S000005554 |
Description of YOR028C: Basic leucine zipper (bZIP) transcription factor of the yAP-1 family; physically interacts with the Tup1-Cyc8 complex and recruits Tup1p to its targets; mediates pleiotropic drug resistance and salt tolerance; nuclearly localized under oxidative stress and sequestered in the cytoplasm by Lot6p under reducing conditions[1][2][3][4]
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References
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- Jump up ↑ Furuchi T, et al. (2001) Two nuclear proteins, Cin5 and Ydr259c, confer resistance to cisplatin in Saccharomyces cerevisiae. Mol Pharmacol 59(3):470-4 SGD PMID 11179441
- Jump up ↑ Hanlon SE, et al. (2011) The Stress Response Factors Yap6, Cin5, Phd1, and Skn7 Direct Targeting of the Conserved Co-Repressor Tup1-Ssn6 in S. cerevisiae. PLoS One 6(4):e19060 SGD PMID 21552514
- Jump up ↑ Mendizabal I, et al. (1998) Yeast putative transcription factors involved in salt tolerance. FEBS Lett 425(2):323-8 SGD PMID 9559673
- Jump up ↑ Sollner S, et al. (2009) Quinone reductase acts as a redox switch of the 20S yeast proteasome. EMBO Rep 10(1):65-70 SGD PMID 19029946
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