YOL156W

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Systematic name YOL156W
Gene name HXT11
Aliases LGT3
Feature type ORF, Verified
Coordinates Chr XV:25273..26976
Primary SGDID S000005516


Description of YOL156W: Putative hexose transporter that is nearly identical to Hxt9p, has similarity to major facilitator superfamily (MFS) transporters and is involved in pleiotropic drug resistance[1][2]




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Community Commentary

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Alleles, Strains, and Phenotypes

Multiple Knockout Strains

Strain Background: CEN.PK2-1C
Genotype: EBY4000 (hxt)
Together with: HXT15, MPH2, HXT7, HXT6, HXT3, HXT13, HXT10, MAL11, HXT4, HXT1, HXT5, HXT12, HXT8, HXT9, HXT16, MPH3, GAL2, HXT2, HXT14, HXT17
Phenotype(s): Viable , Conditionally inviable when on glucose medium

The complete hxt null strain (EBY4000) is unable to take up hexoses and to grow on them. It is well suited to express and characterize heterologous glucose transporters. [3] [4]





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References

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  1. Nourani A, et al. (1997) Multiple-drug-resistance phenomenon in the yeast Saccharomyces cerevisiae: involvement of two hexose transporters. Mol Cell Biol 17(9):5453-60 SGD PMID 9271421
  2. Ozcan S and Johnston M (1999) Function and regulation of yeast hexose transporters. Microbiol Mol Biol Rev 63(3):554-69 SGD PMID 10477308
  3. Wieczorke R, et al. (1999) Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 464(3):123-8 SGD PMID 10618490
  4. submitted by Eckhard Boles on 2003-03-17

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