YOL113W
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| Systematic name | YOL113W |
| Gene name | SKM1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:104326..106293 |
| Primary SGDID | S000005473 |
Description of YOL113W: Member of the PAK family of serine/threonine protein kinases with similarity to Ste20p and Cla4p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth[1][2][3]
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References
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- ↑ Lin M, et al. (2009) The Cdc42 effectors Ste20, Cla4, and Skm1 down-regulate the expression of genes involved in sterol uptake by a mitogen-activated protein kinase-independent pathway. Mol Biol Cell 20(22):4826-37 SGD PMID 19793923
- ↑ Martin H, et al. (1997) Characterization of SKM1, a Saccharomyces cerevisiae gene encoding a novel Ste20/PAK-like protein kinase. Mol Microbiol 23(3):431-44 SGD PMID 9044278
- ↑ Richman TJ, et al. (1999) The Cdc42p GTPase is involved in a G2/M morphogenetic checkpoint regulating the apical-isotropic switch and nuclear division in yeast. J Biol Chem 274(24):16861-70 SGD PMID 10358031
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