YOL110W
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| Systematic name | YOL110W |
| Gene name | SHR5 |
| Aliases | ERF4 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:109176..109889 |
| Primary SGDID | S000005470 |
Description of YOL110W: Subunit of a palmitoyltransferase, composed of Shr5p and Erf2p, that adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; palmitoylation is required for Ras2p membrane localization[1][2][3]
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References
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- Jump up ↑ Dong X, et al. (2003) Palmitoylation and plasma membrane localization of Ras2p by a nonclassical trafficking pathway in Saccharomyces cerevisiae. Mol Cell Biol 23(18):6574-84 SGD PMID 12944483
- Jump up ↑ Roth AF, et al. (2006) Global analysis of protein palmitoylation in yeast. Cell 125(5):1003-13 SGD PMID 16751107
- Jump up ↑ Zhao L, et al. (2002) Erf4p and Erf2p form an endoplasmic reticulum-associated complex involved in the plasma membrane localization of yeast Ras proteins. J Biol Chem 277(51):49352-9 SGD PMID 12379641
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