YOL108C

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Systematic name YOL108C
Gene name INO4
Aliases
Feature type ORF, Verified
Coordinates Chr XV:111886..111431
Primary SGDID S000005468


Description of YOL108C: Transcription factor required for derepression of inositol-choline-regulated genes involved in phospholipid synthesis; forms a complex, with Ino2p, that binds the inositol-choline-responsive element through a basic helix-loop-helix domain[1][2]




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References

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  1. Santiago TC and Mamoun CB (2003) Genome expression analysis in yeast reveals novel transcriptional regulation by inositol and choline and new regulatory functions for Opi1p, Ino2p, and Ino4p. J Biol Chem 278(40):38723-30 SGD PMID 12871953
  2. Schwank S, et al. (1995) Yeast transcriptional activator INO2 interacts as an Ino2p/Ino4p basic helix-loop-helix heteromeric complex with the inositol/choline-responsive element necessary for expression of phospholipid biosynthetic genes in Saccharomyces cerevisiae. Nucleic Acids Res 23(2):230-7 SGD PMID 7862526

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