YOL087C
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| Systematic name | YOL087C |
| Gene name | DUF1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:158637..155287 |
| Primary SGDID | S000005447 |
Description of YOL087C: Ubiquitin-binding protein of unknown function; contains one WD40 repeat in a beta-propeller fold; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; homolog of human WDR48/UAF1, which is involved in regulating the Fanconi anemia pathway; deletion mutant is sensitive to various chemicals including phenanthroline, sanguinarine, and nordihydroguaiaretic acid[1][2][3]
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References
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- ↑ Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
- ↑ Pashkova N, et al. (2010) WD40 repeat propellers define a ubiquitin-binding domain that regulates turnover of F box proteins. Mol Cell 40(3):433-43 SGD PMID 21070969
- ↑ Rieger KJ, et al. (1999) Chemotyping of yeast mutants using robotics. Yeast 15(10B):973-86 SGD PMID 10407277
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