YOL049W

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Systematic name YOL049W
Gene name GSH2
Aliases
Feature type ORF, Verified
Coordinates Chr XV:238619..240094
Primary SGDID S000005409


Description of YOL049W: Glutathione synthetase, catalyzes the ATP-dependent synthesis of glutathione (GSH) from gamma-glutamylcysteine and glycine; induced by oxidative stress and heat shock[1][2][3]




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References

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  1. Grant CM, et al. (1997) Glutathione synthetase is dispensable for growth under both normal and oxidative stress conditions in the yeast Saccharomyces cerevisiae due to an accumulation of the dipeptide gamma-glutamylcysteine. Mol Biol Cell 8(9):1699-707 SGD PMID 9307967
  2. Inoue Y, et al. (1998) Molecular identification of glutathione synthetase (GSH2) gene from Saccharomyces cerevisiae. Biochim Biophys Acta 1395(3):315-20 SGD PMID 9512666
  3. Sugiyama K, et al. (2000) The Yap1p-dependent induction of glutathione synthesis in heat shock response of Saccharomyces cerevisiae. J Biol Chem 275(20):15535-40 SGD PMID 10809786

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