YOL007C
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| Systematic name | YOL007C |
| Gene name | CSI2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:312367..311342 |
| Primary SGDID | S000005367 |
Description of YOL007C: Protein of unknown function; green fluorescent protein (GFP)- fusion protein localizes to the mother side of the bud neck and the vacuole; YOL007C is not an essential gene[1][2]
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Community Commentary
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Transmembrane Domain GxxxG like motif
The transmembrane domain of Csi2p shows homology with the SKG6/AXL2 alpha-helix transmembrane domain (IPR014805). In particular, this domain contains AGclGA. The presence of a GxxxG like motif [3] strongly indicates that Csi2p dimerises.
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References
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- ↑ Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 SGD PMID 12140549
- ↑ Sundin BA, et al. (2004) Localization of proteins that are coordinately expressed with Cln2 during the cell cycle. Yeast 21(9):793-800 SGD PMID 15282802
- ↑ Senes A, Engel DE and DeGrado WF (2004) Folding of helical membrane proteins: the role of polar, GxxxG-like and proline motifs. Curr Opin Struct Biol. 2004 14(4):465-79. PMID 15313242
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