YNR043W
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| Systematic name | YNR043W |
| Gene name | MVD1 |
| Aliases | ERG19 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:701895..703085 |
| Primary SGDID | S000005326 |
Description of YNR043W: Mevalonate pyrophosphate decarboxylase, essential enzyme involved in the biosynthesis of isoprenoids and sterols, including ergosterol; acts as a homodimer[1][2][3]
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References
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- ↑ Berges T, et al. (1997) The Saccharomyces cerevisiae mevalonate diphosphate decarboxylase is essential for viability, and a single Leu-to-Pro mutation in a conserved sequence leads to thermosensitivity. J Bacteriol 179(15):4664-70 SGD PMID 9244250
- ↑ Chambon C, et al. (1991) Sterol pathway in yeast. Identification and properties of mutant strains defective in mevalonate diphosphate decarboxylase and farnesyl diphosphate synthetase. Lipids 26(8):633-6 SGD PMID 1779710
- ↑ Cordier H, et al. (1999) The Saccharomyces cerevisiae mevalonate diphosphate decarboxylase (erg19p) forms homodimers in vivo, and a single substitution in a structurally conserved region impairs dimerization. Curr Microbiol 38(5):290-4 SGD PMID 10355117
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