YNR017W

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Systematic name YNR017W
Gene name TIM23
Aliases MAS6, MIM23, MPI3
Feature type ORF, Verified
Coordinates Chr XIV:662913..663581
Primary SGDID S000005300


Description of YNR017W: Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); involved in protein import into mitochondrial matrix and inner membrane; with Tim17p, contributes to architecture and function of the import channel[1][2][3]




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References

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  1. Emtage JL and Jensen RE (1993) MAS6 encodes an essential inner membrane component of the yeast mitochondrial protein import pathway. J Cell Biol 122(5):1003-12 SGD PMID 8354690
  2. Martinez-Caballero S, et al. (2007) Tim17p regulates the twin pore structure and voltage gating of the mitochondrial protein import complex TIM23. J Biol Chem 282(6):3584-93 SGD PMID 17148445
  3. Truscott KN, et al. (2001) A presequence- and voltage-sensitive channel of the mitochondrial preprotein translocase formed by Tim23. Nat Struct Biol 8(12):1074-82 SGD PMID 11713477

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