YNR011C
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Systematic name | YNR011C |
Gene name | PRP2 |
Aliases | RNA2 |
Feature type | ORF, Verified |
Coordinates | Chr XIV:646950..644320 |
Primary SGDID | S000005294 |
Description of YNR011C: RNA-dependent ATPase in the DEAH-box family, required for activation of the spliceosome before the first transesterification step in RNA splicing; orthologous to human protein DHX16[1][2]
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References
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- ↑ Gencheva M, et al. (2010) Nuclear Retention of Unspliced Pre-mRNAs by Mutant DHX16/hPRP2, a Spliceosomal DEAH-box Protein. J Biol Chem 285(46):35624-32 SGD PMID 20841358
- ↑ Kim SH and Lin RJ (1996) Spliceosome activation by PRP2 ATPase prior to the first transesterification reaction of pre-mRNA splicing. Mol Cell Biol 16(12):6810-9 SGD PMID 8943336
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