YNL272C

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Systematic name YNL272C
Gene name SEC2
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:129084..126805
Primary SGDID S000005216


Description of YNL272C: Guanyl-nucleotide exchange factor for the small G-protein Sec4p; essential for post-Golgi vesicle transport and for autophagy; associates with the exocyst, via exocyst subunit Sec15p, on secretory vesicles[1][2][3]




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References

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  1. Geng J, et al. (2010) Post-golgi sec proteins are required for autophagy in Saccharomyces cerevisiae. Mol Biol Cell 21(13):2257-69 SGD PMID 20444978
  2. Medkova M, et al. (2006) The rab exchange factor Sec2p reversibly associates with the exocyst. Mol Biol Cell 17(6):2757-69 SGD PMID 16611746
  3. Walch-Solimena C, et al. (1997) Sec2p mediates nucleotide exchange on Sec4p and is involved in polarized delivery of post-Golgi vesicles. J Cell Biol 137(7):1495-509 SGD PMID 9199166

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