YNL245C

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Systematic name YNL245C
Gene name CWC25
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:186885..186346
Primary SGDID S000005189


Description of YNL245C: Splicing factor required for the first step of pre-mRNA splicing; binding to the spliceosome requires Prp2p and Yju2p; heat-stable protein; has similarity to S. pombe Cwf25p[1][2][3][4]




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References

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  1. Chiu YF, et al. (2009) Cwc25 is a novel splicing factor required after Prp2 and Yju2 to facilitate the first catalytic reaction. Mol Cell Biol 29(21):5671-8 SGD PMID 19704000
  2. Hazbun TR, et al. (2003) Assigning function to yeast proteins by integration of technologies. Mol Cell 12(6):1353-65 SGD PMID 14690591
  3. Ohi MD, et al. (2002) Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs. Mol Cell Biol 22(7):2011-24 SGD PMID 11884590
  4. Warkocki Z, et al. (2009) Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components. Nat Struct Mol Biol 16(12):1237-43 SGD PMID 19935684

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