YNL222W

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Systematic name YNL222W
Gene name SSU72
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:229094..229714
Primary SGDID S000005166


Description of YNL222W: Transcription/RNA-processing factor that associates with TFIIB and cleavage/polyadenylation factor Pta1p; exhibits phosphatase activity on serine-5 of the RNA polymerase II C-terminal domain; affects start site selection in vivo[1][2][3]




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References

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  1. Krishnamurthy S, et al. (2004) Ssu72 Is an RNA polymerase II CTD phosphatase. Mol Cell 14(3):387-94 SGD PMID 15125841
  2. St-Pierre B, et al. (2005) Conserved and specific functions of mammalian ssu72. Nucleic Acids Res 33(2):464-77 SGD PMID 15659578
  3. Sun ZW and Hampsey M (1996) Synthetic enhancement of a TFIIB defect by a mutation in SSU72, an essential yeast gene encoding a novel protein that affects transcription start site selection in vivo. Mol Cell Biol 16(4):1557-66 SGD PMID 8657130

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