YNL221C

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Systematic name YNL221C
Gene name POP1
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:233695..231068
Primary SGDID S000005165


Description of YNL221C: Subunit of both RNase MRP and nuclear RNase P; RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs; binds to the RPR1 RNA subunit in RNase P[1][2][3][4][5]




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References

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  1. Chamberlain JR, et al. (1998) Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP. Genes Dev 12(11):1678-90 SGD PMID 9620854
  2. Houser-Scott F, et al. (2002) Interactions among the protein and RNA subunits of Saccharomyces cerevisiae nuclear RNase P. Proc Natl Acad Sci U S A 99(5):2684-9 SGD PMID 11880623
  3. Lygerou Z, et al. (1994) The POP1 gene encodes a protein component common to the RNase MRP and RNase P ribonucleoproteins. Genes Dev 8(12):1423-33 SGD PMID 7926742
  4. Marvin MC, et al. (2011) Accumulation of noncoding RNA due to an RNase P defect in Saccharomyces cerevisiae. RNA () SGD PMID 21665995
  5. Tollervey D (1995-1996) Genetic and biochemical analyses of yeast RNase MRP. Mol Biol Rep 22(2-3):75-9 SGD PMID 8901491

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