YNL218W

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Systematic name YNL218W
Gene name MGS1
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:238238..240001
Primary SGDID S000005162


Description of YNL218W: Protein with DNA-dependent ATPase and ssDNA annealing activities involved in maintenance of genome; interacts functionally with DNA polymerase delta; homolog of human Werner helicase interacting protein (WHIP)[1][2][3]




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References

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  1. Branzei D, et al. (2002) The product of Saccharomyces cerevisiae WHIP/MGS1, a gene related to replication factor C genes, interacts functionally with DNA polymerase delta. Mol Genet Genomics 268(3):371-86 SGD PMID 12436259
  2. Hishida T, et al. (2001) A yeast gene, MGS1, encoding a DNA-dependent AAA(+) ATPase is required to maintain genome stability. Proc Natl Acad Sci U S A 98(15):8283-9 SGD PMID 11459965
  3. Hishida T, et al. (2002) Saccharomyces cerevisiae MGS1 is essential in strains deficient in the RAD6-dependent DNA damage tolerance pathway. EMBO J 21(8):2019-29 SGD PMID 11953321

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