YNL121C

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Systematic name YNL121C
Gene name TOM70
Aliases MAS70, MOM72, OMP1
Feature type ORF, Verified
Coordinates Chr XIV:400537..398684
Primary SGDID S000005065


Description of YNL121C: Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; acts as a receptor for incoming precursor proteins[1][2][3][4]




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References

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  1. Brix J, et al. (2000) The mitochondrial import receptor Tom70: identification of a 25 kDa core domain with a specific binding site for preproteins. J Mol Biol 303(4):479-88 SGD PMID 11054285
  2. Meisinger C, et al. (1999) The preprotein translocase of the outer mitochondrial membrane: receptors and a general import pore. Cell Mol Life Sci 56(9-10):817-24 SGD PMID 11212341
  3. Pfanner N, et al. (2004) Assembling the mitochondrial outer membrane. Nat Struct Mol Biol 11(11):1044-8 SGD PMID 15523480
  4. Ryan MT, et al. (2000) The transport machinery for the import of preproteins across the outer mitochondrial membrane. Int J Biochem Cell Biol 32(1):13-21 SGD PMID 10661891

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