YNL107W

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Systematic name YNL107W
Gene name YAF9
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:420098..420778
Primary SGDID S000005051


Description of YNL107W: Subunit of both the NuA4 histone H4 acetyltransferase complex and the SWR1 complex, may function to antagonize silencing near telomeres; interacts directly with Swc4p, has homology to human leukemogenic protein AF9, contains a YEATS domain[1][2]




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References

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  1. Bittner CB, et al. (2004) Direct physical and functional interaction of the NuA4 complex components Yaf9p and Swc4p. Eukaryot Cell 3(4):976-83 SGD PMID 15302830
  2. Zhang H, et al. (2004) The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres. Mol Cell Biol 24(21):9424-36 SGD PMID 15485911

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