YNL106C

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Systematic name YNL106C
Gene name INP52
Aliases SJL2
Feature type ORF, Verified
Coordinates Chr XIV:424495..420944
Primary SGDID S000005050


Description of YNL106C: Polyphosphatidylinositol phosphatase, dephosphorylates a number of phosphatidylinositols (PIs) to PI; involved in endocytosis; hyperosmotic stress causes translocation to actin patches; synaptojanin-like protein with a Sac1 domain[1][2][3][4]




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References

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  1. Guo S, et al. (1999) SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases. J Biol Chem 274(19):12990-5 SGD PMID 10224048
  2. Hughes WE, et al. (2000) Sac phosphatase domain proteins. Biochem J 350 Pt 2():337-52 SGD PMID 10947947
  3. Ooms LM, et al. (2000) The yeast inositol polyphosphate 5-phosphatases inp52p and inp53p translocate to actin patches following hyperosmotic stress: mechanism for regulating phosphatidylinositol 4,5-bisphosphate at plasma membrane invaginations. Mol Cell Biol 20(24):9376-90 SGD PMID 11094088
  4. Singer-Kruger B, et al. (1998) Synaptojanin family members are implicated in endocytic membrane traffic in yeast. J Cell Sci 111 ( Pt 22):3347-56 SGD PMID 9788876

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