YNL097C

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Systematic name YNL097C
Gene name PHO23
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:442358..441366
Primary SGDID S000005041


Description of YNL097C: Probable component of the Rpd3 histone deacetylase complex, involved in transcriptional regulation of PHO5; affects termination of snoRNAs and cryptic unstable transcripts (CUTs); C-terminus has similarity to human candidate tumor suppressor p33(ING1) and its isoform ING3[1][2][3][4][5]




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References

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  1. Gordon PM, et al. (2008) Interspecies data mining to predict novel ING-protein interactions in human. BMC Genomics 9:426 SGD PMID 18801192
  2. Lau WW, et al. (1998) A genetic study of signaling processes for repression of PHO5 transcription in Saccharomyces cerevisiae. Genetics 150(4):1349-59 SGD PMID 9832515
  3. Loewith R, et al. (2000) Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities. Mol Cell Biol 20(11):3807-16 SGD PMID 10805724
  4. Loewith R, et al. (2001) Pho23 is associated with the Rpd3 histone deacetylase and is required for its normal function in regulation of gene expression and silencing in Saccharomyces cerevisiae. J Biol Chem 276(26):24068-74 SGD PMID 11306585
  5. Terzi N, et al. (2011) H3K4 trimethylation by Set1 promotes efficient termination by the Nrd1-Nab3-Sen1 pathway. Mol Cell Biol () SGD PMID 21709022

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