YNL079C
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| Systematic name | YNL079C |
| Gene name | TPM1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:479165..478566 |
| Primary SGDID | S000005023 |
Description of YNL079C: Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; acetylated by the NatB complex and acetylated form binds actin most efficiently[1][2][3]
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References
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- Jump up ↑ Liu HP and Bretscher A (1989) Disruption of the single tropomyosin gene in yeast results in the disappearance of actin cables from the cytoskeleton. Cell 57(2):233-42 SGD PMID 2649250
- Jump up ↑ Pruyne D and Bretscher A (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85 SGD PMID 10652251
- Jump up ↑ Singer JM and Shaw JM (2003) Mdm20 protein functions with Nat3 protein to acetylate Tpm1 protein and regulate tropomyosin-actin interactions in budding yeast. Proc Natl Acad Sci U S A 100(13):7644-9 SGD PMID 12808144
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