YNL076W

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Systematic name YNL076W
Gene name MKS1
Aliases LYS80
Feature type ORF, Verified
Coordinates Chr XIV:483556..485310
Primary SGDID S000005020


Description of YNL076W: Pleiotropic negative transcriptional regulator involved in Ras-CAMP and lysine biosynthetic pathways and nitrogen regulation; involved in retrograde (RTG) mitochondria-to-nucleus signaling[1][2][3][4]




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References

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  1. Edskes HK, et al. (1999) Mks1p is a regulator of nitrogen catabolism upstream of Ure2p in Saccharomyces cerevisiae. Genetics 153(2):585-94 SGD PMID 10511541
  2. Feller A, et al. (1997) Lys80p of Saccharomyces cerevisiae, previously proposed as a specific repressor of LYS genes, is a pleiotropic regulatory factor identical to Mks1p. Yeast 13(14):1337-46 SGD PMID 9392078
  3. Matsuura A and Anraku Y (1993) Characterization of the MKS1 gene, a new negative regulator of the Ras-cyclic AMP pathway in Saccharomyces cerevisiae. Mol Gen Genet 238(1-2):6-16 SGD PMID 8386801
  4. Sekito T, et al. (2002) RTG-dependent mitochondria-to-nucleus signaling is regulated by MKS1 and is linked to formation of yeast prion [URE3]. Mol Biol Cell 13(3):795-804 SGD PMID 11907262

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