YNL053W
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| Systematic name | YNL053W |
| Gene name | MSG5 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:529942..531411 |
| Primary SGDID | S000004998 |
Description of YNL053W: Dual-specificity protein phosphatase; exists in 2 isoforms; required for maintenance of a low level of signaling through the cell integrity pathway, adaptive response to pheromone; regulates and is regulated by Slt2p; dephosphorylates Fus3p[1][2][3]
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References
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- ↑ Blackwell E, et al. (2007) The pheromone-induced nuclear accumulation of the Fus3 MAPK in yeast depends on its phosphorylation state and on Dig1 and Dig2. BMC Cell Biol 8:44 SGD PMID 17963515
- ↑ Doi K, et al. (1994) MSG5, a novel protein phosphatase promotes adaptation to pheromone response in S. cerevisiae. EMBO J 13(1):61-70 SGD PMID 8306972
- ↑ Flandez M, et al. (2004) Reciprocal regulation between Slt2 MAPK and isoforms of Msg5 dual-specificity protein phosphatase modulates the yeast cell integrity pathway. J Biol Chem 279(12):11027-34 SGD PMID 14703512
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