YMR272C

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Systematic name YMR272C
Gene name SCS7
Aliases FAH1
Feature type ORF, Verified
Coordinates Chr XIII:810777..809623
Primary SGDID S000004885


Description of YMR272C: Sphingolipid alpha-hydroxylase, functions in the alpha-hydroxylation of sphingolipid-associated very long chain fatty acids, has both cytochrome b5-like and hydroxylase/desaturase domains, not essential for growth[1][2][3]




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References

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  1. Haak D, et al. (1997) Hydroxylation of Saccharomyces cerevisiae ceramides requires Sur2p and Scs7p. J Biol Chem 272(47):29704-10 SGD PMID 9368039
  2. Hama H, et al. (2000) Requirement of sphingolipid alpha-hydroxylation for fungicidal action of syringomycin E. FEBS Lett 478(1-2):26-8 SGD PMID 10922463
  3. Mitchell AG and Martin CE (1997) Fah1p, a Saccharomyces cerevisiae cytochrome b5 fusion protein, and its Arabidopsis thaliana homolog that lacks the cytochrome b5 domain both function in the alpha-hydroxylation of sphingolipid-associated very long chain fatty acids. J Biol Chem 272(45):28281-8 SGD PMID 9353282

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