YMR271C

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Systematic name YMR271C
Gene name URA10
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:807548..806865
Primary SGDID S000004884


Description of YMR271C: Minor orotate phosphoribosyltransferase (OPRTase) isozyme that catalyzes the fifth enzymatic step in the de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; major OPRTase encoded by URA5[1][2][3][4]




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References

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  1. Denis-Duphil M (1989) Pyrimidine biosynthesis in Saccharomyces cerevisiae: the ura2 cluster gene, its multifunctional enzyme product, and other structural or regulatory genes involved in de novo UMP synthesis. Biochem Cell Biol 67(9):612-31 SGD PMID 2679804
  2. Schmidt R, et al. (1979) Purification and characterization of the hypoxanthine-guanine phosphoribosyltransferase from Saccharomyces cerevisiae. Eur J Biochem 93(2):355-61 SGD PMID 371963
  3. Umezu K, et al. (1971) Purification and properties of orotidine-5'-phosphate pyrophosphorylase and orotidine-5'-phosphate decarboxylase from baker's yeast. J Biochem 70(2):249-62 SGD PMID 5094209
  4. de Montigny J, et al. (1990) Cloning and sequencing of URA10, a second gene encoding orotate phosphoribosyl transferase in Saccharomyces cerevisiae. Curr Genet 17(2):105-11 SGD PMID 2182197

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