YMR264W
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Systematic name | YMR264W |
Gene name | CUE1 |
Aliases | KIS4 |
Feature type | ORF, Verified |
Coordinates | Chr XIII:795805..796416 |
Primary SGDID | S000004877 |
Description of YMR264W: Endoplasmic reticulum membrane protein that recruits the ubiquitin-conjugating enzyme Ubc7p to the ER where it functions in protein degradation; contains a CUE domain that binds ubiquitin to facilitate intramolecular monoubiquitination[1][2]
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References
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- Jump up ↑ Biederer T, et al. (1997) Role of Cue1p in ubiquitination and degradation at the ER surface. Science 278(5344):1806-9 SGD PMID 9388185
- Jump up ↑ Shih SC, et al. (2003) A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain. EMBO J 22(6):1273-81 SGD PMID 12628920
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