YMR229C

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Systematic name YMR229C
Gene name RRP5
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:731123..725934
Primary SGDID S000004842


Description of YMR229C: RNA binding protein with preference for single stranded tracts of U's involved in synthesis of both 18S and 5.8S rRNAs; component of both the ribosomal small subunit (SSU) processosome and the 90S preribosome[1][2][3][4][5][6]




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References

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  1. Dragon F, et al. (2002) A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis. Nature 417(6892):967-70 SGD PMID 12068309
  2. Eppens NA, et al. (1999) The roles of Rrp5p in the synthesis of yeast 18S and 5.8S rRNA can be functionally and physically separated. RNA 5(6):779-93 SGD PMID 10376877
  3. Grandi P, et al. (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15 SGD PMID 12150911
  4. Osheim YN, et al. (2004) Pre-18S ribosomal RNA is structurally compacted into the SSU processome prior to being cleaved from nascent transcripts in Saccharomyces cerevisiae. Mol Cell 16(6):943-54 SGD PMID 15610737
  5. Venema J and Tollervey D (1996) RRP5 is required for formation of both 18S and 5.8S rRNA in yeast. EMBO J 15(20):5701-14 SGD PMID 8896463
  6. de Boer P, et al. (2006) Rrp5p, a trans-acting factor in yeast ribosome biogenesis, is an RNA-binding protein with a pronounced preference for U-rich sequences. RNA 12(2):263-71 SGD PMID 16428605

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