YMR203W

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Systematic name YMR203W
Gene name TOM40
Aliases ISP42, MOM38
Feature type ORF, Verified
Coordinates Chr XIII:668492..669655
Primary SGDID S000004816


Description of YMR203W: Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; constitutes the core element of the protein conducting pore[1][2][3][4][5]




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References

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  1. Chacinska A, et al. (2003) Mitochondrial translocation contact sites: separation of dynamic and stabilizing elements in formation of a TOM-TIM-preprotein supercomplex. EMBO J 22(20):5370-81 SGD PMID 14532110
  2. Meisinger C, et al. (1999) The preprotein translocase of the outer mitochondrial membrane: receptors and a general import pore. Cell Mol Life Sci 56(9-10):817-24 SGD PMID 11212341
  3. Pfanner N, et al. (2004) Assembling the mitochondrial outer membrane. Nat Struct Mol Biol 11(11):1044-8 SGD PMID 15523480
  4. Rapaport D and Neupert W (1999) Biogenesis of Tom40, core component of the TOM complex of mitochondria. J Cell Biol 146(2):321-31 SGD PMID 10427088
  5. Ryan MT, et al. (2000) The transport machinery for the import of preproteins across the outer mitochondrial membrane. Int J Biochem Cell Biol 32(1):13-21 SGD PMID 10661891

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