YMR156C

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Systematic name YMR156C
Gene name TPP1
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:571016..570300
Primary SGDID S000004765


Description of YMR156C: DNA 3'-phosphatase that functions in repair of endogenous damage of double-stranded DNA, activity is specific for removal of 3' phosphates at strand breaks; has similarity to the l-2-haloacid dehalogenase superfamily[1][2]




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References

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  1. Deshpande RA and Wilson TE (2004) Identification of DNA 3'-phosphatase active site residues and their differential role in DNA binding, Mg2+ coordination, and catalysis. Biochemistry 43(26):8579-89 SGD PMID 15222769
  2. Vance JR and Wilson TE (2001) Repair of DNA strand breaks by the overlapping functions of lesion-specific and non-lesion-specific DNA 3' phosphatases. Mol Cell Biol 21(21):7191-8 SGD PMID 11585902

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