YMR115W

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Systematic name YMR115W
Gene name MGR3
Aliases FMP24
Feature type ORF, Verified
Coordinates Chr XIII:497704..499209
Primary SGDID S000004721


Description of YMR115W: Subunit of the mitochondrial (mt) i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins; forms a subcomplex with Mgr1p that binds to substrates to facilitate proteolysis; required for growth of cells lacking mtDNA[1][2]




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References

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  1. Dunn CD, et al. (2008) Mgr3p and Mgr1p are adaptors for the mitochondrial i-AAA protease complex. Mol Biol Cell 19(12):5387-97 SGD PMID 18843051
  2. Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54 SGD PMID 16823961

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