YMR101C

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Systematic name YMR101C
Gene name SRT1
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:469476..468445
Primary SGDID S000004707


Description of YMR101C: Cis-prenyltransferase involved in synthesis of long-chain dolichols (19-22 isoprene units; as opposed to Rer2p which synthesizes shorter-chain dolichols); localizes to lipid bodies; transcription is induced during stationary phase[1][2][3]




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References

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  1. Sato M, et al. (1999) The yeast RER2 gene, identified by endoplasmic reticulum protein localization mutations, encodes cis-prenyltransferase, a key enzyme in dolichol synthesis. Mol Cell Biol 19(1):471-83 SGD PMID 9858571
  2. Sato M, et al. (2001) Yeast Saccharomyces cerevisiae has two cis-prenyltransferases with different properties and localizations. Implication for their distinct physiological roles in dolichol synthesis. Genes Cells 6(6):495-506 SGD PMID 11442630
  3. Schenk B, et al. (2001) An alternative cis-isoprenyltransferase activity in yeast that produces polyisoprenols with chain lengths similar to mammalian dolichols. Glycobiology 11(1):89-98 SGD PMID 11181565

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