YMR079W
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Systematic name | YMR079W |
Gene name | SEC14 |
Aliases | PIT1 |
Feature type | ORF, Verified |
Coordinates | Chr XIII:424989..426059 |
Primary SGDID | S000004684 |
Description of YMR079W: Phosphatidylinositol/phosphatidylcholine transfer protein; involved in regulating PtdIns, PtdCho, and ceramide metabolism, products of which regulate intracellular transport and UPR; functionally homologous to mammalian PITPs[1][2][3]
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References
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- ↑ Mousley CJ, et al. (2008) Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast. Mol Biol Cell 19(11):4785-803 SGD PMID 18753406
- ↑ Schnabl M, et al. (2003) Subcellular localization of yeast Sec14 homologues and their involvement in regulation of phospholipid turnover. Eur J Biochem 270(15):3133-45 SGD PMID 12869188
- ↑ Yanagisawa LL, et al. (2002) Activity of specific lipid-regulated ADP ribosylation factor-GTPase-activating proteins is required for Sec14p-dependent Golgi secretory function in yeast. Mol Biol Cell 13(7):2193-206 SGD PMID 12134061
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