YMR065W

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Systematic name YMR065W
Gene name KAR5
Aliases FIG3
Feature type ORF, Verified
Coordinates Chr XIII:399702..401216
Primary SGDID S000004669


Description of YMR065W: Protein required for nuclear membrane fusion during karyogamy, localizes to the membrane with a soluble portion in the endoplasmic reticulum lumen, may form a complex with Jem1p and Kar2p; expression of the gene is regulated by pheromone[1][2][3]




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References

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  1. Beh CT, et al. (1997) KAR5 encodes a novel pheromone-inducible protein required for homotypic nuclear fusion. J Cell Biol 139(5):1063-76 SGD PMID 9382856
  2. Brizzio V, et al. (1999) Genetic interactions between KAR7/SEC71, KAR8/JEM1, KAR5, and KAR2 during nuclear fusion in Saccharomyces cerevisiae. Mol Biol Cell 10(3):609-26 SGD PMID 10069807
  3. Erdman S, et al. (1998) Pheromone-regulated genes required for yeast mating differentiation. J Cell Biol 140(3):461-83 SGD PMID 9456310

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