YMR013C

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Systematic name YMR013C
Gene name SEC59
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:296738..295179
Primary SGDID S000004615


Description of YMR013C: Dolichol kinase, catalyzes the terminal step in dolichyl monophosphate (Dol-P) biosynthesis; required for viability and for normal rates of lipid intermediate synthesis and protein N-glycosylation[1][2]




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References

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  1. Bernstein M, et al. (1989) Sec59 encodes a membrane protein required for core glycosylation in Saccharomyces cerevisiae. Mol Cell Biol 9(3):1191-9 SGD PMID 2657387
  2. Heller L, et al. (1992) Saccharomyces cerevisiae sec59 cells are deficient in dolichol kinase activity. Proc Natl Acad Sci U S A 89(15):7013-6 SGD PMID 1323123

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