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Systematic name YML129C
Gene name COX14
Feature type ORF, Verified
Coordinates Chr XIII:14753..14541
Primary SGDID S000004598

Description of YML129C: Mitochondrial membrane protein, involved in translational regulation of Cox1p and assembly of cytochrome c oxidase (complex IV); associates with complex IV assembly intermediates and complex III/complex IV supercomplexes[1][2][3]


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Protein Details

Other Protein Details

Other Topic: Regulated by the diauxic shift (glycerol)

Apart form the overall increase in mitochondrial protein mass after the diauxic shift this protein remains unchanged after the diauxic shift. [4] [5]


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  1. Barrientos A, et al. (2004) Mss51p and Cox14p jointly regulate mitochondrial Cox1p expression in Saccharomyces cerevisiae. EMBO J 23(17):3472-82 SGD PMID 15306853
  2. Glerum DM, et al. (1995) Cloning and characterization of COX14, whose product is required for assembly of yeast cytochrome oxidase. J Biol Chem 270(26):15585-90 SGD PMID 7797555
  3. Mick DU, et al. (2007) Shy1 couples Cox1 translational regulation to cytochrome c oxidase assembly. EMBO J 26(20):4347-58 SGD PMID 17882259
  4. Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
  5. submitted by Steffen Ohlmeier on 2004-04-08

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