YML110C

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Systematic name YML110C
Gene name COQ5
Aliases DBI56
Feature type ORF, Verified
Coordinates Chr XIII:50954..50031
Primary SGDID S000004578


Description of YML110C: 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase, involved in ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with other ubiquinone biosynthetic enzymes[1][2][3]




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References

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  1. Barkovich RJ, et al. (1997) Characterization of the COQ5 gene from Saccharomyces cerevisiae. Evidence for a C-methyltransferase in ubiquinone biosynthesis. J Biol Chem 272(14):9182-8 SGD PMID 9083049
  2. Dibrov E, et al. (1997) The COQ5 gene encodes a yeast mitochondrial protein necessary for ubiquinone biosynthesis and the assembly of the respiratory chain. J Biol Chem 272(14):9175-81 SGD PMID 9083048
  3. Hsieh EJ, et al. (2007) Saccharomyces cerevisiae Coq9 polypeptide is a subunit of the mitochondrial coenzyme Q biosynthetic complex. Arch Biochem Biophys 463(1):19-26 SGD PMID 17391640

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