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Systematic name YML074C
Gene name FPR3
Aliases NPI46
Feature type ORF, Verified
Coordinates Chr XIII:121324..120089
Primary SGDID S000004539

Description of YML074C: Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase); FK506 binding protein; phosphorylated by casein kinase II (Cka1p-Cka2p-Ckb1p-Ckb2p) and dephosphorylated by Ptp1p[1][2][3]


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  1. Benton BM, et al. (1994) A novel FK506- and rapamycin-binding protein (FPR3 gene product) in the yeast Saccharomyces cerevisiae is a proline rotamase localized to the nucleolus. J Cell Biol 127(3):623-39 SGD PMID 7525596
  2. Shan X, et al. (1994) Yeast NPI46 encodes a novel prolyl cis-trans isomerase that is located in the nucleolus. J Cell Biol 126(4):853-62 SGD PMID 8051210
  3. Wilson LK, et al. (1997) Casein kinase II catalyzes tyrosine phosphorylation of the yeast nucleolar immunophilin Fpr3. J Biol Chem 272(20):12961-7 SGD PMID 9148902

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