YLR404W

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Systematic name YLR404W
Gene name FLD1
Aliases SEI1
Feature type ORF, Verified
Coordinates Chr XII:928743..929600
Primary SGDID S000004396


Description of YLR404W: Seipin protein involved in lipid droplet morphology, number, and size; proposed to be involved in lipid metabolism; related to the human BSCL2 which is associated with lipodystrophy[1][2]




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References

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  1. Fei W, et al. (2008) Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast. J Cell Biol 180(3):473-82 SGD PMID 18250201
  2. Szymanski KM, et al. (2007) The lipodystrophy protein seipin is found at endoplasmic reticulum lipid droplet junctions and is important for droplet morphology. Proc Natl Acad Sci U S A 104(52):20890-5 SGD PMID 18093937

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