YLR380W

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Systematic name YLR380W
Gene name CSR1
Aliases SFH2
Feature type ORF, Verified
Coordinates Chr XII:878282..879508
Primary SGDID S000004372


Description of YLR380W: Phosphatidylinositol transfer protein with a potential role in regulating lipid and fatty acid metabolism under heme-depleted conditions; interacts specifically with thioredoxin peroxidase; may have a role in oxidative stress resistance[1][2][3]




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References

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  1. Cha MK, et al. (2003) The protein interaction of Saccharomyces cerevisiae cytoplasmic thiol peroxidase II with SFH2p and its in vivo function. J Biol Chem 278(37):34952-8 SGD PMID 12824182
  2. Desfougeres T, et al. (2008) SFH2 regulates fatty acid synthase activity in the yeast Saccharomyces cerevisiae and is critical to prevent saturated fatty acid accumulation in response to haem and oleic acid depletion. Biochem J 409(1):299-309 SGD PMID 17803462
  3. Schnabl M, et al. (2003) Subcellular localization of yeast Sec14 homologues and their involvement in regulation of phospholipid turnover. Eur J Biochem 270(15):3133-45 SGD PMID 12869188

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