YLR362W
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| Systematic name | YLR362W |
| Gene name | STE11 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:849866..852019 |
| Primary SGDID | S000004354 |
Description of YLR362W: Signal transducing MEK kinase involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p[1][2][3][4]
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References
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- ↑ Grimshaw SJ, et al. (2004) Structure of the sterile alpha motif (SAM) domain of the Saccharomyces cerevisiae mitogen-activated protein kinase pathway-modulating protein STE50 and analysis of its interaction with the STE11 SAM. J Biol Chem 279(3):2192-201 SGD PMID 14573615
- ↑ Neiman AM and Herskowitz I (1994) Reconstitution of a yeast protein kinase cascade in vitro: activation of the yeast MEK homologue STE7 by STE11. Proc Natl Acad Sci U S A 91(8):3398-402 SGD PMID 8159759
- ↑ O'Rourke SM and Herskowitz I (1998) The Hog1 MAPK prevents cross talk between the HOG and pheromone response MAPK pathways in Saccharomyces cerevisiae. Genes Dev 12(18):2874-86 SGD PMID 9744864
- ↑ Rhodes N, et al. (1990) STE11 is a protein kinase required for cell-type-specific transcription and signal transduction in yeast. Genes Dev 4(11):1862-74 SGD PMID 2276621
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